Postmenopausal osteoporosis : hormones and other therapies

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The risks of hormone therapy may also vary depending on whether estrogen is given alone or with progestin, the dose and type of estrogen, and other health factors such as your risks of heart and blood vessel cardiovascular disease, cancer risks, and family medical history.

All of these risks should be considered in deciding whether hormone therapy might be an option for you. Despite its health risks, systemic estrogen is still the most effective treatment for menopausal symptoms.

The benefits of hormone therapy may outweigh the risks if you're healthy and you:. Women who experience early menopause, particularly those who had their ovaries removed and don't take estrogen therapy until at least age 45, have a higher risk of:. For women who reach menopause prematurely, the protective benefits of hormone therapy usually outweigh the risks.

Your age, type of menopause and time since menopause play significant roles in the risks associated with hormone therapy. Talk with your doctor about your personal risks.

Menopausal Hormone Therapy 2014- Dr. Stephanie Faubion 7/23/14

Women who have or previously had breast cancer, ovarian cancer, endometrial cancer, blood clots in the legs or lungs, stroke, liver disease, or unexplained vaginal bleeding should usually not take hormone therapy. If you aren't bothered by menopausal symptoms and started menopause after age 45, you do not need hormone therapy to stay healthy.

Instead, talk to your doctor about strategies to reduce the risk of conditions such as osteoporosis and heart disease. These strategies might include lifestyle changes and medications other than hormone therapy for long-term protection. If you haven't had a hysterectomy and are using systemic estrogen therapy, you'll also need progestin.

Your doctor can help you find the delivery method that offers the most benefits and convenience with the least risks and cost.

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You may be able to manage menopausal hot flashes with healthy-lifestyle approaches, such as keeping cool, limiting caffeinated beverages and alcohol, and practicing paced relaxed breathing or other relaxation techniques. For vaginal concerns, such as dryness or painful intercourse, a vaginal moisturizer or lubricant may provide relief. You might also ask your doctor about the prescription medication ospemifene Osphena , which may help with episodes of painful intercourse.


To determine if hormone therapy is a good treatment option for you, talk to your doctor about your individual symptoms and health risks. Be sure to keep the conversation going throughout your menopausal years. As researchers learn more about hormone therapy and other menopausal treatments, recommendations may change. If you continue to have bothersome menopausal symptoms, review treatment options with your doctor on a regular basis.

Postmenopausal Osteoporosis: Hormones & Other Therapies - CRC Press Book

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Hormone therapy: Is it right for you? Products and services. Free E-newsletter Subscribe to Housecall Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Sign up now. By Mayo Clinic Staff. References Pinkerton JV, et al. De Villiers TJ, et al. Revised global consensus statement on menopausal hormone therapy.

Facts about menopausal hormone therapy.

Coherence treatment of postmenopausal osteoporosis with growth hormone and calcitonin

National Heart, Lung, and Blood Institute. Accessed April 12, Fourteen women with postmenopausal osteoporosis, all having at least one vertebral crush fracture, were randomly assigned to two treatment arms, each lasting 24 months.

Breast cancer

The coherence treatment group 7 patients was treated in the following sequence: human growth hormone hGH 7 IU subcutaneously daily for 2 months, followed by 3 months of salmon calcitonin CT , MRC units every other day. After a 3 month rest period, this sequence was repeated twice.

Parathyroid Hormone for Treatment of Osteoporosis

The contrast group 7 patients was treated intermittently with salmon CT given in the same time periods and at the same dose as in the coherence treatment group. Bone mass was measured every 4 months by neutron activation analysis for total body calcium TBCa and by single photon absorptiometry for bone mineral content BMC of the distal radius. The increase in bone mass appeared to be sustained throughout the 2 year study, in contrast with previous studies where a plateau effect was observed with calcitonin given alone or continuously with growth hormone. No significant change was found in bone histomorphometric values measured before and after treatment in 4 patients from each group.

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